Why is meeting the mdr for thiamin important
Vitamin requirements of elderly people: an update. Am J Clin Nutr. The influence of vitamin B2 intake on the activation coefficient of erythrocyte glutation reductase in the elderly.
J Nutr Health Aging. Gariballa S, Ullegaddi R. Riboflavin status in acute ischaemic stroke. Eur J Clin Nutr. Low dietary riboflavin but not folate predicts increased fracture risk in postmenopausal women homozygous for the MTHFR T allele. J Bone Miner Res. Vitamin B-6 requirements of elderly men and women. J Nutr. Vitamin C concentrations in plasma as a function of intake: a meta-analysis. Int J Vitam Nutr Res. Age-related decline of sodium-dependent ascorbic acid transport in isolated rat hepatocytes.
Arch Biochem Biophys. Dietary vitamin K intakes are associated with hip fracture but not with bone mineral density in elderly men and women. Age-related decreases in chromium levels in 51, hair, sweat, and serum samples from 40, patients--implications for the prevention of cardiovascular disease and type II diabetes mellitus. Mineral requirements of elderly people. Iron status of the free-living, elderly Framingham Heart Study cohort: an iron-replete population with a high prevalence of elevated iron stores.
Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for vitamin A, vitamin K, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. Washington, D. The National Academies Press. Modern Nutrition in Health and Disease. Dietary reference intakes for vitamin C, vitamin E, selenium, and carotenoids.
National Academy Press. EFSA J. Geneva: WHO; American Heart Association. Frequently Asked Questions About Fish. Age-dependent decrease of carnitine content in muscle of mice and humans.
Biochem Biophys Res Commun. Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity. Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. Savitha S, Panneerselvam C. Mitochondrial membrane damage during aging process in rat heart: potential efficacy of L-carnitine and DL alpha lipoic acid. Mech Ageing Dev. Efficacy of levo carnitine and alpha lipoic acid in ameliorating the decline in mitochondrial enzymes during aging.
Clin Nutr. Sethumadhavan S, Chinnakannu P. L-carnitine and alpha-lipoic acid improve age-associated decline in mitochondrial respiratory chain activity of rat heart muscle.
Carnitine and lipoic acid alleviates protein oxidation in heart mitochondria during aging process. Sundaram K, Panneerselvam KS. Oxidative stress and DNA single strand breaks in skeletal muscle of aged rats: role of carnitine and lipoicacid.
Age-associated deficit of mitochondrial oxidative phosphorylation in skeletal muscle: role of carnitine and lipoic acid. Mol Cell Biochem. Supplementation of L-carnitine improves mitochondrial enzymes in heart and skeletal muscle of aged rats. Exp Aging Res. Oxidative stress-mediated macromolecular damage and dwindle in antioxidant status in aged rat brain regions: role of L-carnitine and DL-alpha-lipoic acid.
Clin Chim Acta. Mitochondrial aging: open questions. Ann N Y Acad Sci. Age-related changes in the lipid compositions of rat and human tissues. Alho H, Lonnrot K. Coenzyme Q supplementation and longevity. In: Kagan V, Quinn P, eds. Effect on absorption and oxidative stress of different oral Coenzyme Q10 dosages and intake strategy in healthy men. Effect of coenzyme Q10 intake on endogenous coenzyme Q content, mitochondrial electron transport chain, antioxidative defenses, and life span of mice.
Free Radic Biol Med. Life-long supplementation with a low dosage of coenzyme Q10 in the rat: effects on antioxidant status and DNA damage.
The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice. J Neurochem. Learning ability in aged beagle dogs is preserved by behavioral enrichment and dietary fortification: a two-year longitudinal study. Neurobiol Aging. Alpha-lipoic acid as a new treatment option for Azheimer type dementia. Arch Gerontol Geriatr. A randomized, double-blind, placebo-controlled trial of deprenyl and thioctic acid in human immunodeficiency virus-associated cognitive impairment.
Flavonoid permeability across an in situ model of the blood-brain barrier. Protective effect of flavonoids against aging- and lipopolysaccharide-induced cognitive impairment in mice. Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model.
Nutr Neurosci. Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation. J Neurosci. Blueberry supplemented diet: effects on object recognition memory and nuclear factor-kappa B levels in aged rats. Intake of flavonoids and risk of dementia. Eur J Epidemiol. Dietary intake of antioxidants and risk of Alzheimer disease. Dietary antioxidants and Parkinson disease.
The Rotterdam Study. Arch Neurol. Brain aging and midlife tofu consumption. Midlife dietary intake of antioxidants and risk of late-life incident dementia: the Honolulu-Asia Aging Study.
Am J Epidemiol. Flavonoid intake and cognitive decline over a year period. Effect of soy protein containing isoflavones on cognitive function, bone mineral density, and plasma lipids in postmenopausal women: a randomized controlled trial. Psychological assessment of the effects of treatment with phytoestrogens on postmenopausal women: a randomized, double-blind, crossover, placebo-controlled study. Fertil Steril. Heilbronn LK, Ravussin E. Calorie restriction and aging: review of the literature and implications for studies in humans.
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate.
Curr Biol. Resveratrol improves health and survival of mice on a high-calorie diet. Donate to the MIC. Subscribe to our Research Newsletter. The Linus Pauling Institute's Micronutrient Information Center provides scientific information on the health aspects of dietary factors and supplements, food, and beverages for the general public. The information is made available with the understanding that the author and publisher are not providing medical, psychological, or nutritional counseling services on this site.
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For media contact information. Skip to main content. Toggle menu Go to search page. Search Field. You are here Life Stages » Older Adults. Older Adults. Table 1. Table 2. American Heart Association recommendation The American Heart Association recommends that people without documented coronary heart disease CHD eat a variety of fish preferably oily at least twice weekly Dietary factors L-carnitine Age-related declines in mitochondrial function and increases in mitochondrial oxidant production are thought to be important contributors to the adverse effects of aging.
Coenzyme Q 10 According to the free radical and mitochondrial theories of aging, oxidative damage of cell structures by reactive oxygen species ROS plays an important role in the functional declines that accompany aging People also need more during pregnancy and while breastfeeding.
It is available in several forms, and the vitamin A content in foods is often measured as retinol activity equivalents RAEs. The recommended daily allowances of vitamin A by age are as follows:. During pregnancy, the requirement is mcg per day.
While breastfeeding, it is 1, mcg per day. People who use the weight loss drug orlistat may have a higher risk of deficiency. Vitamin A supplements are available for those whose bodies have difficulty absorbing the nutrient, but it is best to meet needs through food, where possible.
This is because the use of supplements can mask possible deficiencies of other nutrients. This may lead to further health issues. Preformed vitamin A can be toxic when people consume too much, either through their diet or through supplementation. The tolerable upper intake level for vitamin A varies by age.
The upper intake level is the amount above which vitamin A intake may be toxic. The list below details the upper intake levels for preformed vitamin A by age:.
It does not appear that a person can consume too much beta-carotene, as the body will only convert it into vitamin A as necessary. That said, consuming too much preformed vitamin A can lead to vitamin A toxicity, or hypervitaminosis A.
Symptoms can include :. The use of the topical treatment retinol may also increase vitamin A levels to an unhealthy level.
People tend to use retinol as an anti-aging skin cream. Topical products can have adverse effects on the skin, though these will likely be less severe than those resulting from oral overconsumption.
However, people should avoid using them during pregnancy. The highest risk of overconsumption is with supplements. A healthful, balanced diet is unlikely to lead to toxic levels of vitamin A. It should also provide enough vitamin A without needing supplements. Another possible cause of vitamin A toxicity is the use of retinol-based medications.
Isotretinoin Accutane is one such example. Doctors sometimes prescribe isotretinoin for severe acne. Anyone using this treatment should avoid taking vitamin A supplements because this drug is a vitamin A derivative. Learn more about the adverse effects of Accutane here. Vitamin A is an essential nutrient that contributes to many functions in the body, such as protecting eye health. In the U. Most people can meet their needs for vitamin A through their diet. In some cases, however, a doctor may recommend supplements.
How long do vitamins last? Here, learn whether they expire and whether it is safe to take vitamin supplements after their expiration dates. All vegetables provide key vitamins, minerals, and fiber, but some offer more health benefits than others. Learn about 15 of the most healthful…. Retinol can help reduce the appearance of wrinkles, acne, cellulite, and more.
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